This book is a valuable tool to assist both cardiovascular physicians and scientists learning the intricacies of hypertension research and its milestone studies. All major hypertension trials have been reviewed in this book in chronological order with extensive discussion of the study population, study design, and outcomes and with a special focus on what knowledge they offered, their strengths and weaknesses, statistical errors, impact on international guidelines and unmet needs. Importantly, the book also offers physicians and young scientists with basic knowledge regarding medical biostatistics. It is of critical importance for a scientist involved in the field to understand deeply the process of analyzing medical data. Moreover, the accurate interpretation of the results is central for applying evidence-based medicine in everyday clinical practice.
Management of Hypertension: Current Practice and the Application of Landmark Trials is a critical tool to assist in the education of physicians and researchers in the field, providing a separate section on pioneer researchers in hypertension and urging readers to become bright exemplars for scientists wishing to pursue a career in academic medicine and hypertension research.
- The Importance of Applying Evidence-Based Medicine in Clinical Practice
- Medical Biostatics: Basic Concepts
- Arterial Hypertension and Cardiovascular Risk
- The VA Cooperative Studies; The First RCTs in Cardiovascular Disease: A Tribute to Edward D. Freis
- The Role of Dietary Modifications in Controlling Blood Pressure
- Hypertension Management in the Elderly
- Management of Hypertension in Diabetes Mellitus
- Chronic Kidney Disease and Hypertension
- Hypertension Management in African Americans: The AASK and Other Landmark Trial Application
- Comparison Therapies in The Treatment of Hypertension. The ASCOT and ACCOMPLISH Trials
- Outcomes of different antihypertensive regimens
- Advantages and Disadvantages in Clinical Trials
- Arterial Hypertension: What is the Optimal Goal of Treatment?
- Methods of Blood Pressure Assessment Used in Milestone Hypertension Trials
- The Life and the Major Scientific Contributions of Irvine Page
- Neurogenic Mechanisms in Pre-hypertension and Pharmacologic Approaches to the Prevention and Treatment of Hypertension: Highlights of Professor Stevo Julius’ Scientific Contributions
- New Frontiers in Cardiovascular Research: Microfluidic Modeling of Cardiovascular Diseases and Applications for Hypertension Research
Dr Vasilios Papademetriou, MD, is a professor of medicine at Georgetown University School of Medicine, and staff cardiologist at Veterans Affairs Medical Centre in Washington, DC. He is the director of cardiovascular research, interventional hypertension and vascular medicine program, and co-director of the Cardiac Catheterization Laboratory at the Veterans Affairs Medical Centre. Dr Papademetriou’s clinical interests include cardiac catheterization, PCI/STENTS, myocardial biopsies, pericardiocentesis, stress and transesophageal echocardiography, and revascularization of high risk patients. He runs a large clinic of patients with resistant hypertension and dyslipidemia, while his research is focused on hypertension and vascular biology, dyslipidemia, atherosclerosis, acute coronary syndromes/acute MI, and cardiovascular complications of diabetes. He has special interest in device-based treatment of patients with resistant hypertension and he is one of the principal investigators of the Renal Denervation projects. He has been a principal investigator for many “investigator initiated” and multicenter clinical trials and received numerous research grants from both public funding and industrial sponsors.
Dr Emmanuel A. Andreadis, MD, PhD is the director of the Fourth Department of Internal Medicine and the Head of the Hypertension and Cardiovascular Disease Prevention Center at Evangelismos General Hospital, in Athens, Greece, which has been recognized as an ESH Center of Excellence since 2012. Recently, Dr Andreadis and the Center became affiliated with the Hypertension and Vascular Medicine Clinic of the Veterans Affairs Medical Center, in Washington, DC, USA. He trained extensively in hypertension at the University Department of Medicine & Therapeutics and the Glasgow Blood Pressure Clinic, Western Infirmary, Glasgow, UK, and he is an ESH Clinical Hypertension Specialist. He is also a European Fellow on Medical Angiology having trained at the Saint Mary’s Hospital, in London, UK. Dr Andreadis is a member of the European Society of Hypertension and the Hellenic Society of Hypertension. His research focuses on hypertension and especially on blood pressure monitoring. He is a highly talented and experienced clinician, with over 35 years of experience in hospital and clinic settings in both acute and primary care. He is highly familiar with the diagnosis and treatment of multiple disease states and health concerns.
Dr Charalampia V. Geladari, MD is a senior Internal Medicine Resident and a Research Fellow at the Hypertension and Cardiovascular Prevention Clinic, Fourth Department of Internal Medicine at Evangelismos General Hospital, in Athens, Greece, and also at the Hypertension and Vascular Medicine Clinic, of the Veterans Affairs Medical Center, in Washington, DC, USA. She has previously been a postdoctoral cardiovascular fellow at Beth Israel Deaconess Medical Center, Harvard University, Boston Massachusetts.